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Title

THE FLY SAGA: HOW DROSOPHILA BECAME THE QUEEN OF GENETICS

Content

I am sure you all must have heard about Marie Kondo through a very popular and recent web series, she is a Japanese organizing consultant who uses a special type of tidying method for cleaning and organizing cluttered houses. Kondo’s name has been used by a group of scientists from the United States and Canada to name a recently discovered protein in Drosophila melanogaster which plays a very similar role in its embryonic development as Kondo plays in real life. The Marie Kondo protein, which is a part of ubiquitin-proteasome system and works as an E2 ubiquitin enzyme, has a role of clearing up three maternally derived proteins during maternal-to-zygotic transition (MZT). But this story which I am narrating is not about the Marie Kondo protein, it is about Drosophila or the fruit flies in which this important discovery was made. The importance and use of the Drosophila sp. as an animal model has revolutionized the field of genetics and molecular biology. In 1909, T.H. Morgan used the fruit flies for the first time in his laboratory. Since that day many milestone discoveries have been made in the field, I am going to enumerate some of these in this article.

Create Date

8/10/2024 6:44:07 AM

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